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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e4979bec3dcd42c666e6eae363f750b91c10ceffd2544b139d2b699c0180230' 
  AND token = 'qQLcD2AKxkJrYLP2rcynv3GNU+vy7+A8JOv6UoN+tuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}