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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e76f4255cc553a4444e73c6eab3cc993a270581c1ae151f4329b46b65fc862' 
  AND token = 'ejU51OBL6pDPuuuXiH3Y9nzFe0xR3yf5PGbMp6soMiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}