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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457fd8bbe156418a80f1bc0be59fb66439140e8650e6b7df1f68c3d4c07cab03' 
  AND token = 'SdEhUYW9YPiBh9FkpMeZYBgVav0vIRS9M8nj7v0ncUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}