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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cb0de12efeaaef3c0ba6e854e8de209e275b9675c1728a22c1eb956e12fe097' 
  AND token = 'Rnl85p2oosqqeVuaw25lyusRPVDvi44L5cKcDFlGwSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}