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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a3c563150aa8f6bcc1442ef00fd8292989f06a0c077af60285783065a0134a' 
  AND token = 'dEjyYhB16OTps08Kptw9wB0U2DZlsAYs1lp1oOoibqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}