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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6e628c541d160dc16a075430bf8d6b290b2201143b651360f85746461414c80' 
  AND token = 'IGMZRSU6Y5jt21i3vMR1QoeICOJIXDimL7I9pJY0ncs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}