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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f909f73ed042f68d404109a9d7c2c3107ac019dae60017bf11d67b90bce8fbec' 
  AND token = 'DekFrewzfru6haaQOudVhzisKyhxcgo8K8WgtcJlU78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}