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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2acc4c9e5d4b93b41d747212f91f8c3d0dbef43cc188bc5770c58dbd6bfe7349' 
  AND token = 'DdR7lA/vxXhhEH0CVO+jfmry8rY5aWcBy4itvvZKd3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}