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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eda10d8e1765fde641c0feca4c9e4b5992948f4e20985787615de584f63f299' 
  AND token = 'gRfh0gUA8FgLZT6pw/x5KG/AzaZXUu2NWHTkucvfbyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}