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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd452b8e3658e3741814c3832332f2f967bc7c7d1a4902ce1fc10a8b85012494d' 
  AND token = 'tS+BNVElcwQlaY7BpYNSh0iItcoAH884jwf2ZiKn6bY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}