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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '797d0a3228b02aa816e1aca1b0b58ad8faab3721ad66db2b39516a4cdb23e8a4' 
  AND token = '1VPGsV2T8W6JzRrFjYItRPDH2MRQvBBDot0xpFqMalQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}