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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1fe0709c182ee0b05447cfbfdd697a907c7ebdc48e73def2b97b5dac90e03d5' 
  AND token = 'nndj4g6k4ETmZ3HrJeGT/jyHqnkQ4VG/0DGIL158Xh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}