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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d9f468363117cef91c1555efeae91a85575f70f42359b5579ee6b4d9dfb6749' 
  AND token = 'PZJoXzmwJHF1HNAmxQJcWZ6z8oNWlpBzZ6SnwBHuQjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}