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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d2a8860a9b55e0e916e5a32e82a819f3a2d0360ffbde1221029fd18904673e1' 
  AND token = 'n261lMT8ntIymlloyFrbPvB0UnDeGqEhB0l6al16AoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}