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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c78bf893a27453d41e629291e5f6fd1f23f0cb888cd02cefefc2a6dba3a9252' 
  AND token = '2OSmN04XLr1oi9LqtJLSqoxOoF++6hqOUd158W67xhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}