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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06f1701da754ce208be1e40893d5247b4ae4299a616938c67943a100af44b603' 
  AND token = 'ZOwe0XVuzRgFyiBNdRWYiyb4Crb4uTbYhxfQB4aZ5+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}