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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd075f4b2e783cd516ccd132567fa10b228eb7e1cb9b13d031ee708375d33840a' 
  AND token = 'sxV36ef2suZZRmg1GEfmKa8x/Sxx/z4mvCyX2UnVBgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}