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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '589353addc4de682c23d1d3a6f55c7bc7a2c7f738011985e3b756ca48c0cfe43' 
  AND token = 'cTxVEs5R0yJZlKJMQ19xUiFVs44ZhVAm6K4BSgBPtP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}