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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95d946bc86d17cf17ecbec70f47ec5389bbf6ef8e45113d53efb8a8fe3c49296' 
  AND token = 'ayMLI4+2EKyWWo0o4QV2Bif8Gm5/6SEvR4NwAg/qQKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}