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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d0bdd6ceb125f198aa1a854ce446d3fd2824998868a4259b78f549aef7e9a22' 
  AND token = 'D8jJewPEe7a3GyRBJtklLyNaeZquUCKYLrrTlfFCYXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}