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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09cbdf4b8a64a3725111131934fe4e909086a0bfefc1aafdb7e8c103fa9f8720' 
  AND token = '/IZCfr2MwkusRQlquPQjvXUyF9FlvqQD5ufEEzsRwt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}