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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '336137e9e7779d07d0b6ea045707da8d9fe7d81e5b02dce5bc686e8ee1879cd4' 
  AND token = 'jcYBFDKmnuOKq3o5x3JB9v4G9V/mWpRfRD55QeY73z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}