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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c272a23a08de94a38155ab7b55b5e351c3f8e9f54c273eb527168a6b7c621d62' 
  AND token = 'UuikZ/DQvkG2cYFVZFHakELDvNfYPa8upj800oJS3DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}