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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cbb97fadea3418fd6d8e9d0d71453f77c75fb3fa56ddcbe1c86c9151b3526d4' 
  AND token = 'ydZNNvvSqTi0HUdqzEdFnW8zh9bXf2VEUhCgg8nOwt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}