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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33dee0d652a1e6f2c2da2606f2ff609f165287e29671b038292ea8fbcb384a7e' 
  AND token = 'mr69FWZtzcnrW6lVGF5z3BQKUc/GgxHbm20gHDpB0Fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}