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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e068c300bcefe3fcabe2fa6456e7b88a74ce6d48bd70def5c8dd4352e9b0581a' 
  AND token = 'Hd34X3sekuFrpyB5jSmjinTxi1c9585d8mAgzzwrdcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}