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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '424e0446eb36a7ac7a269cda3fa98ab51d293353c74292f67ae4b3dcefe968c5' 
  AND token = '34Atd7mm4OK4LBo5KseHSy7IuQnRjSKp5BfP3fn2wBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}