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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7118ef78e48ea8d333c4171409c864b25e8b2f70281e8e47f8c64aaed71b2f69' 
  AND token = '8NZb5pRh5O6XkrfmZ0yLOlN/IXZzKzVoWzHsHnKI2es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}