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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43605d5938b5477cd3720aa7fc7bfeaecaf5a40b238c6009e4635e018c1aee9e' 
  AND token = 'KHG811my8eCChokWVyt3YehftuVxUd5ySzEMEy7JYw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}