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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c04c3d02e97d489b5962ce2a92a309d7148a6bccd51fb30f82c335229876c7ad' 
  AND token = 'JAVp8GUQ6ynyBa6JMVQHFzm8bKqwRSlBCQmka3WDrk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}