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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '570610f14a9df57b0d49ce565783dfa599c41cd7a85100c0761b566080b44c54' 
  AND token = 'QrrQrWBMAEfQF8aKg5lo5suFIwm1e1hUA58FOdUgFwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}