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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16cc449fac13fc1fd08a1bb24ce4c6d5e3f7ecff4bfa0dd8e2c9ff34b3785fb4' 
  AND token = 'HC+PRRZXIXiPQpSyT7vd0eP4V14v5ii+LliO9hEUWgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}