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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149c53a98863bf8ad8c66435c604e1c9bd723c42e69f8e70e46851c85dc80f3a' 
  AND token = 'y22CseJOK8S3oDXDcOFuyaJ4LHgRGMBR4gWyG0PY5y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}