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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca09f3e52d602624eb7dd40941fb7203350889ff1aa3bc0d23a6d2d9dda887f' 
  AND token = 'Q4UAHgp9N5wo7O2z3l6tC4p4Iiz22cjYlMw5IyK8y0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}