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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e09f486e42a7dde7b69f50eed8e5cc8d1ab057224f5045ec24724e6854501b5' 
  AND token = 'GtzR5cyLSeJyQp7Gt50e/cTms8X3CA8ByH0MG+a5d0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}