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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a74abc2b92c643a1a71d78dfd57eb824e66b334249b19f6d434bd5c0735a30cf' 
  AND token = 'KI0qFiWIXHVSaZ2VivWH1LyfeEdUQb/zVywr3ke4p4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}