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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0b1d7df003b5a3aea8e7a11b592d871efd7091fad0cf0a79d1b61eb8b86bf8a' 
  AND token = '6RA+vKYx2fVuqsY22nN5pLLVq8vq0fU0ACRJAOeKX5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}