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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48de6c8cf0630d4be90d4f24b83664e1c7da3fdb0bba49eb3d8fdf30bfe85b2f' 
  AND token = '7GVcMFVjbMEoTzFZFJN0XhQV+97LQDux9RC7R/h2WjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}