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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a152de5811e383596350ebaebe93e7a37c4ac9b0f4ca4b02c4fd7a344d8c12' 
  AND token = 't43FoW82U8jnMAckzjeGitnET5urXR83rbef0M/QnIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}