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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab20f18d1b755d504a50cc4857f0b4554d5ce8f4207d06373f0aa3cc99fe2c0f' 
  AND token = 'CN8uRJEbmg8E7m4GtjGSo53e+VmQpeUnqfw2j5QmCwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}