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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6905c87dd9b10e78bf2ffb4bba3878240b7e6edd9a106a855b0ab03012d47f66' 
  AND token = '/sqHWrNbRHEhu1Vu4TXWLUJe7nb1ffOC1KzYFZNSkm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}