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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83333f3db5b89d5f4c6a0a36d756dc0562058a59e2bb4f5eac244766c2db0fb8' 
  AND token = 'Jyk9mbnGbfpwtXckvk4JDoZY9u8UdQJT5gtMhk9tEZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}