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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c269555fb2c5756a36df2ef96c3b3417e8e6f03d02d22146dbb6ec44ec061e14' 
  AND token = '/kMt4/Nu7P3Npfo6FoYxqTiVRA3GF8xrtuDqmc7JjkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}