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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'add4a2a8712ae7b10215755ec889fade97bcb782652cfbec2dfe9a1413103cb3' 
  AND token = 'EW3TBLdd2fqa/3vU6c2V0JHLc/BQpR4cpfmjpobaBWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}