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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '485c814b44b19394a92c1874e544e4575b7f8315ba38fec083aac8ca87a4ecc7' 
  AND token = 'xPY+MgbmHNgbwQX7FqXTMrebShLxcCzgRLxgON6RGB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}