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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729c53d9e90644828ebe1001f81e650fe9debb131493a724a4db0b7da64ca1b1' 
  AND token = 'ieSL1msRdHlyZNUHX9SQdc2gT/lKE48Ci62krcNkPLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}