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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0404bb0f1c98df74786b5c0d15dbd3d2a542deb1f7a1b0a2c517a7afc64a6b29' 
  AND token = 'PU9Eb00f9gidsSzhkRea3D8+6yIwmtsUg40IfPK248w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}