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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7ef13d821a64d113a82dfea13bd6553f20cf17098a88e748667215a66ee8964' 
  AND token = 'E0z+Mhf8xWg4dCt6+cx2BHV7EYc0036KxhByce33yHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}