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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afe506ba44da9aa2b63a3e69784277f4cf3aac09b0c735034948dd462307ae6a' 
  AND token = 'sMfdpGJ/ajs/d2Bh+yDweovp5A6IjfU+8IO3sXmuiiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}