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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dd279548f0a6bbeed6634934afdd91c51d76028b91e60522013bb0ec1be8b2b' 
  AND token = 'Donw/vmsG59252tAQr3N/g1EPdGl92jPG1abt7PsxzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}